Place pretzels in a food processor and pulse until pretzels turn to crumbs. Or you can put the pretzels in a large zip up bag and use a rolling pin, frying pan or meat tenderizer to turn the pretzels into crumbs. Put the pretzels into a bowl.
Add flour to a bowl with garlic powder, onion powder, salt and pepper. Stir together.
Assemble the bowls from left to right starting with the seasoned flour, eggs then pretzel crumbs.
Line a baking sheet with aluminum foil.
Dredge a piece of chicken in the flour, then eggs and finally the pretzel crumbs. Make sure to coat all sides of the chicken. Place the chicken on a baking sheet. Repeat with the remaining chicken.