Preheat the oven to 375 degrees F. Spray an 8x8 baking dish with nonstick cooking spray.
Season the chicken breasts with garlic powder, onion powder, salt, and pepper.
Spray a nonstick pan with cooking spray and sear the chicken breasts for 2-3 minutes on both sides over medium-high heat. Remove from the heat.
In a small bowl, mix cream cheese, Greek yogurt, grated Parmesan cheese, and minced garlic until smooth.
Place chicken breasts in the baking dish. Spread the creamy garlic cheese mixture evenly over one side of each chicken breast.
Bake uncovered for 20-25 minutes, or until the chicken breast reaches an internal temperature of 165 degrees F.
Optional: Garnish with parsley or chives.